In a dreary, dim and nondescript room, Clov draws the curtains from the windows and prepares his master Hamm for his day. He says, "It's nearly finished," though it is not clear what he is referring to. He awakes Hamm by pulling a sheet from over him. After Hamm removes a bloodstained handkerchief from over his head and face, he says "It's time it ended." He summons Clov by means of a whistle, and they banter briefly.
Eventually, Hamm's parents, Nell and Nagg, appear from inside two trash cans at the back of the stage. Hamm is as equally threatening, condescending and acrimonious with his parents as with his servant, though they still share a degree of mutual humor; Nell eventually sinks back into her bin, and Clov, examining her, says, "She has no pulse." Hamm tells his father he is telling a story and recites it partially to him, a fragment which treats on a derelict man who comes crawling on his belly to the narrator, who is putting up Christmas decorations, begging him for food for his starving boy sheltering in the wilderness.
Clov returns, and they continue to banter in a way that is both quick-witted and comical yet with dark, overt existential undertones. Clov often threatens to leave Hamm, but it is made clear that he has nowhere to go as the world outside seems to be destroyed. Much of the stage action is intentionally banal and monotonous, including sequences where Clov moves Hamm's chair in various directions so that he feels himself to be in the right position, as well as moving him nearer to the window.
By the end of the play, Clov finally seems intent on pursuing his commitment of leaving his cruel master Hamm. Clov tells him there is no more of the painkiller left, which Hamm has been insisting on getting his dose of throughout the play. Hamm finishes his dark, chilling story by having the narrator berate the collapsed man for the futility of trying to feed his son for a few more days when evidently their luck has run out (it becomes plain that the character of the narrator is Hamm himself, relating the events which brought Clov [the man's son] to him). Hamm believes Clov has left, being blind, but Clov re-enters and stands in the room silently with his coat on and carrying luggage, going nowhere. Hamm calls for his father, but receives no answer; he discards some of his belongings, and says that, though he has made his exit, his bloodstained handkerchief, which he replaces over his face and head, will "remain".
