- Speak (band), a synthpop band from Austin, Texas
- "Speak" (Bachelor Girl song), a 2018 single by Australian pop band Bachelor Girl
- "Speak" (Godsmack song), a 2006 song by the band Godsmack
- Speak (Jimmy Needham album), 2006
- Speak (Lindsay Lohan album), the debut album by the actress Lindsay Lohan
- Speak (Londonbeat album), the debut album by the British-American dance band Londonbeat, 1988
- "Speak" (Nickel Creek song), a single by progressive bluegrass band Nickel Creek
- Speak (I and Thou album), 2012
- Speak (No-Man album), a compilation album by No-Man
- Speak (The Roches album), 1989
- Speak (Warren Dean Flandez album), 2018
- Speak!, a weekday sports talk show formerly called Speak for Yourself
- Speak!!!, an American rapper and songwriter
- "Speak", a song by Sevendust from Sevendust
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